Combining D’Liver’s in vitro and in vivo assays will determine the exact mechanisms behind liver uptake, providing strategic consulting aiding in accelerating and improving the development of a compound.
D’Liver provides tailored in vivo liver uptake studies of biologics and nanopharmaceuticals, as well as general pharmacokinetic, biodistribution and liver cell toxicology assays.
With D’Liver’s unique expertise in the preparation of highly purified hepatocytes, Kupffer cells and liver sinusoidal endothelial cells we determine the exact cellular sites of liver uptake, metabolism and toxicology of compounds.
With the use of D’Liver’s integrated scientific and technical expertise in the preparation of freshly and highly purified cultured liver cells, the interaction with the compound can be effectively explored.